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[LEFT]Materials Safety Data Sheets - CHLOROFORM
Department of Chemical Technology
1
CHLOROFORM
MSDS Number: C2915 — Effective Date: 09/15/98

  1. Product Identification
    Synonyms: Trichloromethane; Methyl trichloride; Methane trichloride
    CAS No.: 67-66-3
    Molecular Weight: 119.38
    Chemical Formula: CHCl3
    Product Codes:
    J.T. Baker: 9174, 9175, 9180, 9181, 9182, 9183, 9184, 9186, 9257
    Mallinckrodt: 1473, 2175, 4432, 4434, 4439, 4440, 4441, 4443, 4444, H407, V551
  2. Composition/Information on Ingredients
    Ingredient CAS No Percent Hazardous

Chloroform 67-66-3 98 - 100% Yes
Ethyl Alcohol 64-17-5 0 - 1% Yes
3. Hazards Identification
Emergency Overview

DANGER! MAY BE FATAL IF SWALLOWED, INHALED OR ABSORBED
THROUGH SKIN. CAUSES IRRITATION TO SKIN, EYES AND RESPIRATORY
TRACT. MAY AFFECT CENTRAL NERVOUS SYSTEM, CARDIOVASCULAR
SYSTEM, LIVER AND KIDNEYS. SUSPECT CANCER HAZARD. MAY CAUSE
CANCER. Risk of cancer depends on level and duration of exposure.
J.T. Baker SAF-T-DATA™ Ratings (Provided here for your convenience)

Health Rating: 3 - Severe (Cancer Causing)
Flammability Rating: 0 - None
Reactivity Rating: 1 - Slight
Contact Rating: 2 - Moderate
Lab Protective Equip: GOGGLES & SHIELD; LAB COAT & APRON; VENT HOOD;
PROPER GLOVES
Storage Color Code: Blue (Health)

Potential Health Effects

Inhalation:
Acts as a relatively potent anesthetic. Irritates respiratory tract and causes central nervous
system effects, including headache, drowsiness, dizziness. Exposure to higher
concentrations may result in unconsciousness and even death. May cause liver injury and
Materials Safety Data Sheets - CHLOROFORM
Department of Chemical Technology
2
blood disorders. Prolonged exposure may lead to death due to irregular heart beat and
kidney and liver disorders.
Ingestion:
Causes severe burning in mouth and throat, pain in the chest and vomiting. Large quantities
may cause symptoms similar to inhalation.
Skin Contact:
Causes skin irritation resulting in redness and pain. Removes natural oils. May be absorbed
through skin.
Eye Contact:
Vapors causes pain and irritation to eyes. Splashes may cause severe irritation and possible
eye damage.
Chronic Exposure:
Prolonged or repeated exposure to vapors may cause damage to the nervous system, the
heart and the liver and kidneys. Contact with liquid has defatting effect and may cause
chronic irritation of skin with cracking and drying, and corresponding dermatitis.
Chloroform is a suspected human carcinogen.
Aggravation of Pre-existing Conditions:
Persons with pre-existing skin disorders or eye problems, or impaired liver, kidney or
respiratory function may be more susceptible to the effects of the substance.
4. First Aid Measures
Inhalation:
Remove to fresh air. If not breathing, give artificial respiration. If breathing is difficult,
give oxygen. Get medical attention.
Ingestion:
If swallowed, DO NOT INDUCE VOMITING. Give large quantities of water. Never give
anything by mouth to an unconscious person. Get medical attention immediately.
Skin Contact:
Immediately flush skin with plenty of water for at least 15 minutes while removing
contaminated clothing and shoes. Get medical attention immediately. Wash clothing before
reuse. Thoroughly clean shoes before reuse.
Eye Contact:
Immediately flush eyes with plenty of water for at least 15 minutes, lifting lower and upper
eyelids occasionally. Get medical attention immediately.
Note to Physician:
Because kidney and liver effects may be delayed, keep victim under observation for 24 to
48 hr. Administration of fluids may help to prevent kidney failure. Obtain blood glucose,
urinalysis, liver function tests, chest x-ray, and monitor cardiac function and
fluid/electrolyte status. Monitor liver and kidney function for 4 to 5 days after exposure.
Disulfiram, its metabolites, and a high carbohydrate diet appear to protect somewhat
against chloroform toxicity. Do not give adrenalin! Tests may show increased bilirubin,
ketosis, lowered blood prothombin, and fibrogen.
5. Fire Fighting Measures
Fire:
Slight fire hazard when exposed to high heat; otherwise, practically not flammable.
Explosion:
Materials Safety Data Sheets - CHLOROFORM
Department of Chemical Technology
3
Sealed containers may rupture when heated.
Fire Extinguishing Media:
Use any means suitable for extinguishing surrounding fire.
Special Information:
In the event of a fire, wear full protective clothing and NIOSH-approved self-contained
breathing apparatus with full facepiece operated in the pressure demand or other positive
pressure mode.
6. Accidental Release Measures
Ventilate area of leak or spill. Wear appropriate personal protective equipment as specified
in Section 8. Isolate hazard area. Keep unnecessary and unprotected personnel from
entering. Contain and recover liquid when possible. Collect liquid in an appropriate
container or absorb with an inert material (e. g., vermiculite, dry sand, earth), and place in a
chemical waste container. Do not use combustible materials, such as saw dust. Do not flush
to sewer! US Regulations (CERCLA) require reporting spills and releases to soil, water
and air in excess of reportable quantities. The toll free number for the US Coast Guard
National Response Center is (800) 424-8802.
J. T. Baker SOLUSORB® solvent adsorbent is recommended for spills of this product.
7. Handling and Storage
Keep in a tightly closed light-resistant container, stored in a cool, dry, ventilated area.
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